NIH-funded research NIH-funded research

Understanding how nicotine affects tobacco use and public health.

Official title: The Ohio State University Tobacco Center of Regulatory Science (OSU-TCORS)

Funded at Ohio State University · NIH-10929345 · Data updated 2026-11-12

This study looks at how the tobacco industry uses nicotine to make their products more addictive, especially for young people, and explores ways to help reduce tobacco use and keep everyone healthier.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startSeptember 14, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$3,904,159
NIH project number5U54CA287392-02
Project IDNIH-10929345 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals under 21 years old who are current or potential users of tobacco products.

Less likely to help

Patients who are not using tobacco products or are over the age of 21 may not receive direct benefits from this research.

What this research studies

This research investigates the role of nicotine in tobacco products, focusing on how the tobacco industry manipulates nicotine levels to increase addiction and usage among different demographics, particularly young people. It examines various nicotine delivery methods, including e-cigarettes and oral nicotine pouches, and how regulatory measures can be used to control these products' appeal and addiction potential. By analyzing the industry's strategies, the research aims to develop effective public health interventions to reduce tobacco use and improve population health outcomes.

Why it matters

Potential benefit: If successful, this research could lead to more effective regulations that reduce tobacco use and its associated health risks, particularly among young people.

How similar studies have gone: Previous research has shown that regulating nicotine levels can significantly impact tobacco use behaviors, indicating that this approach has potential for success.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Wagener, Theodore Lee — Ohio State University
  • Study coordinator: Wagener, Theodore Lee

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.