Understanding how nicotine affects the brain and body to control its intake
Nicotine & Nodose: A Neural Basis for Peripheral Control over Nicotine Intake
This study is looking at how nicotine affects the brain and body to better understand addiction, with the hope of finding new ways to help people quit smoking.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10866435 on NIH RePORTER |
What this research studies
This research investigates the complex relationship between nicotine addiction and its effects on both the brain and body. It explores how nicotine interacts with specific brain circuits and whether it also influences nicotine intake through peripheral sensory inputs. By using advanced techniques, including CRISPR, the study aims to uncover the neural mechanisms that regulate nicotine consumption, which could lead to new strategies for treating nicotine addiction. Patients may benefit from insights that could inform better cessation therapies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals struggling with nicotine addiction or those interested in understanding the biological mechanisms behind nicotine intake.
Not a fit: Patients who do not use nicotine or have no interest in quitting smoking may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for nicotine addiction, potentially reducing smoking rates and associated health risks.
How similar studies have performed: Other research has shown promising results in understanding the neural mechanisms of addiction, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Braunscheidel, Kevin — Icahn School of Medicine at Mount Sinai
- Study coordinator: Braunscheidel, Kevin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.