Understanding how newborn brains adapt and respond to treatments
Individualized Mechanisms of Neural Plasticity and Response to Interventions in Neonates
['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-10979637
This study is looking at how newborns' brains grow and change, especially to help kids who might face mental health challenges later on, so we can find the best ways to support them early on when their brains are most flexible.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-10979637 on ClinicalTrials.gov |
What this research studies
This research investigates how the brains of newborns develop and change, particularly in relation to psychiatric disorders that can affect children. By focusing on the early stages of brain development, the study aims to identify specific brain networks that are most adaptable and responsive to interventions. Researchers will measure changes in brain activity week by week to personalize treatment strategies for high-risk infants. The goal is to implement preventative measures early in life when the brain is most capable of change.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns identified as high-risk for developing psychiatric disorders due to family history or other factors.
Not a fit: Patients who are older than infancy or those without a predisposition to psychiatric disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to early interventions that significantly reduce the risk of developing psychiatric disorders in children.
How similar studies have performed: Previous research has shown promise in understanding brain plasticity in infants, but this specific approach is novel and aims to personalize interventions.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SYLVESTER, CHAD MICHAEL — WASHINGTON UNIVERSITY
- Study coordinator: SYLVESTER, CHAD MICHAEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.