Understanding how new tuberculosis infections spread in Kampala, Uganda
Capturing spatial patterns of new M. tuberculosis infection in Kampala, Uganda
['FUNDING_R01'] · CASE WESTERN RESERVE UNIVERSITY · NIH-10894025
This study is looking at how new tuberculosis infections spread in Kampala, Uganda, and aims to find ways to prevent it by checking the blood of people who may be at higher risk, especially those who have been around TB patients, so we can help keep the community healthy.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CASE WESTERN RESERVE UNIVERSITY (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-10894025 on ClinicalTrials.gov |
What this research studies
This research investigates the patterns of new tuberculosis (TB) infections in Kampala, Uganda, focusing on how to prevent the spread of the disease. It aims to identify individuals at high risk for developing active TB by analyzing biomarkers in their blood. By understanding these patterns and using targeted preventive therapy, the research seeks to reduce the incidence of TB in the community. The study will involve community members, particularly those who have been in contact with TB patients.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals living in Kampala who have been in close contact with TB patients or are at high risk for TB infection.
Not a fit: Patients who are not in contact with TB patients or those who have already developed active TB may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the number of new TB cases and improve health outcomes in high-risk populations.
How similar studies have performed: Previous research has shown success in using biomarkers to identify individuals at risk for TB progression, indicating that this approach has potential for effective intervention.
Where this research is happening
CLEVELAND, UNITED STATES
- CASE WESTERN RESERVE UNIVERSITY — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BARK, CHARLES MARTYN — CASE WESTERN RESERVE UNIVERSITY
- Study coordinator: BARK, CHARLES MARTYN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus