Understanding how new brain cells help with memory and spatial awareness
Role of Adult Neurogenesis in Spatial Information Encoding in the Dentate Gyrus
['FUNDING_R01'] · ALBERT EINSTEIN COLLEGE OF MEDICINE · NIH-11080196
This study is looking at how new brain cells help adults remember things and navigate their surroundings, using special imaging to see these cells in action, which could help us understand memory better and find ways to help people with memory problems.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALBERT EINSTEIN COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (BRONX, UNITED STATES) |
| Trial ID | NIH-11080196 on ClinicalTrials.gov |
What this research studies
This research investigates the role of new neurons formed in the dentate gyrus of the brain and how they contribute to memory and spatial awareness in adults. By using advanced imaging techniques like 2-photon microscopy, the study aims to observe the activity of these neurons in real-time as they engage in behaviors that require spatial memory. The researchers will manipulate the levels of neurogenesis to see how it affects the brain's ability to encode spatial information, providing insights into the mechanisms behind memory discrimination. This could lead to a better understanding of cognitive functions and potential interventions for memory-related disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who may be experiencing cognitive challenges or are interested in understanding memory processes.
Not a fit: Patients with severe neurological disorders that significantly impair cognitive function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing memory and cognitive function in adults.
How similar studies have performed: Previous research has shown promising results regarding the role of neurogenesis in cognitive functions, suggesting that this approach could yield significant insights.
Where this research is happening
BRONX, UNITED STATES
- ALBERT EINSTEIN COLLEGE OF MEDICINE — BRONX, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GONCALVES, JOSE TIAGO — ALBERT EINSTEIN COLLEGE OF MEDICINE
- Study coordinator: GONCALVES, JOSE TIAGO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.