Understanding how new brain cells are formed in adults

Continuous Neurogenesis in the Mammalian Hippocampus

NIH-funded research University of Pennsylvania · NIH-11092006

This study is looking at how new brain cells are made in adults, especially in a part of the brain that helps with learning and memory, and it aims to find out how this process works in hopes of helping people with brain injuries or diseases.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11092006 on NIH RePORTER

What this research studies

This research investigates the process of adult neurogenesis, which is the formation of new neurons in the hippocampus, a brain region essential for learning and memory. The study employs advanced techniques to explore the origins of these new neurons and their integration into the existing brain structure. By using rodent models, researchers aim to uncover the mechanisms that support neurogenesis and how these processes might differ in humans. The findings could provide insights into potential therapies for brain injuries and neurodegenerative diseases.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults experiencing cognitive decline or those interested in brain health and neurogenesis.

Not a fit: Patients with acute neurological conditions or those who are not adults may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that enhance brain repair and cognitive function in adults.

How similar studies have performed: Previous studies have shown promising results in understanding neurogenesis, but this research aims to explore new methodologies that have not been extensively tested.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.