Understanding how neutrophils help heal wounds
Official title: Neutrophil heterogeneity and plasticity in wound healing
Funded at University of Wisconsin-Madison · NIH-10894247 · Data updated 2026-11-12
This study is looking at how certain immune cells called neutrophils help heal wounds, especially after severe burns, to find out how they change over time and how that might help doctors improve treatments for patients with serious injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | August 5, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $375,430 |
| NIH project number | 5R35GM150893-02 |
| Project ID | NIH-10894247 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced severe burn injuries and are undergoing treatment.
✕Less likely to help
Patients with minor injuries or those not experiencing complications from wounds may not benefit from this research.
What this research studies
This research investigates the different types of neutrophils, which are key immune cells, and how they function in various tissues during the wound healing process. By using advanced techniques like single-cell profiling and bioinformatics, the study aims to map out the specific roles and behaviors of neutrophils in response to injuries, particularly severe burn injuries. The goal is to identify how these cells change over time and how their characteristics can predict complications in healing. This could lead to better treatment strategies for patients with severe wounds.
Why it matters
Potential benefit: If successful, this research could improve wound healing outcomes and reduce complications for patients with severe burn injuries.
How similar studies have gone: Other research has shown promising results in understanding immune cell behavior in wound healing, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Dinh, Huy Quang — University of Wisconsin-Madison
- Study coordinator: Dinh, Huy Quang
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.