Understanding how neurotransmitters are transported in the brain
Deciphering the Molecular Mechanisms of Neurotransmitter Transport
This study is looking into how brain chemicals are moved around in our nervous system, which is important for helping people with conditions like depression, anxiety, autism, and addiction, to find better treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10993176 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms behind neurotransmitter transport, which is crucial for treating various neurological disorders like depression, anxiety, autism, and addiction. The team will explore how synaptic vesicles, which store neurotransmitters, function and how they are affected by different substances, including addictive drugs. By using advanced biochemical and biophysical techniques, the researchers aim to uncover the details of how these transport proteins operate, which could lead to better treatments for patients suffering from these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with neurological disorders such as depression, anxiety, autism, or those struggling with addiction.
Not a fit: Patients with neurological conditions not related to neurotransmitter transport or those who do not have access to the research facilities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for neurological disorders and addiction, enhancing patient outcomes.
How similar studies have performed: Previous research has shown promise in understanding neurotransmitter systems, but this specific focus on synaptic vesicle transporters is relatively novel.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Coleman, Jonathan — University of Pittsburgh at Pittsburgh
- Study coordinator: Coleman, Jonathan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.