Understanding how neurotransmitters are released in the brain
Official title: Mechanistic Principles of SNARE Disassembly in Neurotransmitter Release
Funded at Stanford University · NIH-11009508 · Data updated 2026-11-12
This study is looking at how certain proteins in the brain help send messages between nerve cells, which could help us understand more about brain function and mental health.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | December 11, 2023 |
| Project end | December 10, 2025 |
| Funding year | 2025 |
| Award (this year) | $42,690 |
| NIH project number | 5F31MH134477-02 |
| Project ID | NIH-11009508 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing cognitive or mental health issues related to neurotransmitter dysfunction.
✕Less likely to help
Patients with neurological conditions unrelated to neurotransmitter release mechanisms may not benefit from this research.
What this research studies
This research investigates the mechanisms behind neurotransmitter release in the brain, focusing on the role of SNARE proteins and their disassembly process. By studying how these proteins interact and function during synaptic transmission, the research aims to uncover the fundamental principles that govern communication between neurons. The approach involves biochemical assays and biological models to analyze the dynamics of SNARE disassembly and its impact on neurotransmitter availability. This knowledge could provide insights into complex brain behaviors and mental health conditions.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for mental illnesses and cognitive disorders by improving our understanding of neurotransmitter release.
How similar studies have gone: Previous research has shown promising results in understanding synaptic transmission mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Khan, Yousuf a — Stanford University
- Study coordinator: Khan, Yousuf a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.