Understanding how neuropeptide receptors affect alcohol's impact on behavior
Neuropeptide receptors, behavioral states and acute ethanol effects
This study is looking at how certain receptors in the nervous system affect how alcohol changes behavior, using tiny worms as a model, to help us understand more about alcohol use disorders and why some people react differently to drinking.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-10827403 on NIH RePORTER |
What this research studies
This research investigates how specific neuropeptide receptors in the nervous system influence the effects of alcohol on behavior. By studying the model organism C. elegans, the researchers aim to identify which receptors are involved in both normal movement and the behavioral changes induced by alcohol consumption. The study will also explore how different behavioral states can affect sensitivity to alcohol, potentially leading to a better understanding of alcohol use disorders. Through this comprehensive approach, the research seeks to uncover the biological mechanisms that underlie alcohol's effects on behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who struggle with alcohol use or have a history of alcohol-related behavioral issues.
Not a fit: Patients who do not consume alcohol or have no interest in understanding alcohol's effects on behavior may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into the biological factors that contribute to alcohol use disorders, potentially informing treatment strategies.
How similar studies have performed: While the specific approach of this research is novel, previous studies have shown success in understanding the role of neuropeptides in substance use behaviors.
Where this research is happening
Richmond, United States
- Virginia Commonwealth University — Richmond, United States (Active)
Researchers
- Principal investigator: Davies, Andrew G — Virginia Commonwealth University
- Study coordinator: Davies, Andrew G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.