Understanding how neurons manage energy for brain activity
How do neurons coordinate alternative energy sources to meet the demands of computation?
This study looks at how brain cells manage their energy needs while they work, using both fruit flies and humans to understand how they predict what energy they'll need based on what they're doing, which could help us learn more about how energy use affects how our brains function and behave.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10983340 on NIH RePORTER |
What this research studies
This research investigates how neurons in the brain coordinate different energy sources to support their computational demands. By examining the relationship between neural activity and energy production, the study aims to uncover how neurons predict their future energy needs based on current activity levels. The research utilizes advanced imaging techniques and models to explore these processes in both fruit flies and human brain activity. This could provide insights into how energy efficiency impacts brain function and behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who may have conditions affecting brain function or energy metabolism.
Not a fit: Patients with acute neurological injuries or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of brain energy management, potentially informing treatments for neurological disorders.
How similar studies have performed: Previous research has shown promising results in understanding energy dynamics in neural activity, suggesting that this approach could yield valuable insights.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Clandinin, Thomas Robert — Stanford University
- Study coordinator: Clandinin, Thomas Robert
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.