Understanding how neurons develop their shape
Investigating the molecular mechanisms of early neuronal morphogenesis
This study is looking at how a special protein called Unkempt helps shape nerve cells, which is important for their job in the brain, and the findings could help us understand more about brain development and related conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Riverside NIH-funded |
| Lab location | 1 site (Riverside, United States) |
| Project ID | NIH-11002671 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms that guide the development of neuronal shape, which is crucial for their function. By studying a specific RNA-binding protein called Unkempt, the researchers aim to uncover how this protein influences the morphology of neurons and other cell types. The approach involves examining the interactions of Unkempt with other cellular components to understand its role in shaping cells. Patients may benefit from insights gained about neuronal development and potential implications for neurological disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with neurological disorders or developmental issues related to neuronal function.
Not a fit: Patients with conditions unrelated to neuronal morphology or function may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating neurological disorders linked to abnormal neuronal morphology.
How similar studies have performed: Other research has shown promising results in understanding cellular morphology, but the specific mechanisms explored in this study are novel.
Where this research is happening
Riverside, United States
- University of California Riverside — Riverside, United States (Active)
Researchers
- Principal investigator: Murn, Jernej — University of California Riverside
- Study coordinator: Murn, Jernej
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.