Understanding how neural circuits synchronize in the brain
Application of the principle of symmetry to neural circuitry: From building blocks to neural synchronization in the connectome
This study is looking at how brain cells work together in tiny worms called C. elegans to help scientists better understand brain activity, and it will create a new tool to make it easier for researchers to analyze these connections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | City College of New York NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10006982 on NIH RePORTER |
What this research studies
This research aims to explore the building blocks of neural circuits by applying mathematical principles to understand how these circuits synchronize. Using a model organism, C. elegans, which has a fully mapped nervous system, the researchers will observe brain activity at a single-cell level in real-time. They will develop a software tool to help neuroscientists analyze these neural circuits and their functions. The study combines theoretical modeling with experimental validation to uncover the relationship between neural structure and function.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with neurological conditions or those interested in the underlying mechanisms of brain function.
Not a fit: Patients with conditions unrelated to neural circuitry or those not residing in the geographic area of the research may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into brain function and potential treatments for neurological disorders.
How similar studies have performed: While the application of symmetry in neural circuits is a novel approach, similar studies have shown promise in understanding brain dynamics and synchronization.
Where this research is happening
New York, United States
- City College of New York — New York, United States (Active)
Researchers
- Principal investigator: Makse, Hernan — City College of New York
- Study coordinator: Makse, Hernan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.