Understanding how nerve cells transport materials at branch points
Regulation of Axonal Transport At Branch Junctions
This study looks at how tiny proteins help move important materials along nerve cells, especially at points where the cells branch out, to better understand how our nervous system develops and heals after injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10828748 on NIH RePORTER |
What this research studies
This research investigates the mechanisms of axonal transport, which is crucial for the development and function of the nervous system. It focuses on how motor proteins move essential materials along nerve cell structures, particularly at branch junctions where these structures diverge. By examining the interactions between these proteins and the cellular framework, the research aims to uncover how materials are selectively directed into growing branches of nerve cells. This could provide insights into the regulation of neuronal connectivity and regeneration after injury.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with neurological conditions that affect axonal transport, such as epilepsy or other seizure disorders.
Not a fit: Patients with conditions unrelated to axonal transport or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating neurological disorders by enhancing nerve cell repair and function.
How similar studies have performed: Previous research has shown promising results in understanding axonal transport mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
Philadelphia, United States
- Thomas Jefferson University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Ma, Le — Thomas Jefferson University
- Study coordinator: Ma, Le
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.