Understanding how nerve cells release signaling molecules
Cellular mechanisms of peptidergic signaling
This study is looking at how nerve cells release important chemicals that affect things like pain and emotions, which could help us understand conditions like depression, diabetes, and chronic pain better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11011200 on NIH RePORTER |
What this research studies
This research investigates the cellular mechanisms that control the release of peptide transmitters from nerve cells, which are crucial for various physiological processes including pain sensation and emotional responses. By exploring how these signaling molecules are secreted, the study aims to uncover the complex pathways involved, particularly focusing on the role of G protein-coupled receptors. Patients may benefit from insights gained into how compromised signaling can lead to conditions like depression, diabetes, and chronic pain. The research employs advanced biological assays and techniques to analyze these mechanisms in detail.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from chronic pain, depression, or metabolic disorders.
Not a fit: Patients with acute pain conditions or those not affected by the signaling pathways being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for conditions related to pain and emotional disorders.
How similar studies have performed: Other research has shown promising results in understanding neuropeptide signaling, suggesting that this approach could yield significant insights.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Banghart, Matthew R. — University of California, San Diego
- Study coordinator: Banghart, Matthew R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.