Understanding how nerve cells influence regeneration in animals
Molecular and cellular mechanisms underlying the nerve dependence of regeneration
This study is looking at how some animals, like the axolotl and Spanish ribbed newt, can regrow lost body parts, and it hopes to find helpful information that could improve healing and recovery for people with injuries or conditions that affect their bodies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia Univ New York Morningside NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10876280 on NIH RePORTER |
What this research studies
This research investigates the molecular and cellular mechanisms that enable certain animals, like the axolotl, to regenerate lost body parts. By examining how different cell types interact and communicate during the regeneration process, the study aims to uncover the fundamental principles that govern tissue repair and regeneration. The research utilizes a model organism, the Spanish ribbed newt, to explore these mechanisms in detail, providing insights that could be applicable across various species. Patients may benefit from advancements in regenerative medicine derived from this research.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions that impair healing or regeneration, such as severe injuries or degenerative diseases.
Not a fit: Patients with conditions unrelated to tissue regeneration or those who do not have regenerative capabilities may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in regenerative medicine, potentially improving healing and recovery for patients with injuries or degenerative conditions.
How similar studies have performed: Previous research has shown promising results in understanding regeneration mechanisms in model organisms, indicating that this approach has potential for significant advancements.
Where this research is happening
New York, United States
- Columbia Univ New York Morningside — New York, United States (Active)
Researchers
- Principal investigator: Tosches, Maria Antonietta — Columbia Univ New York Morningside
- Study coordinator: Tosches, Maria Antonietta
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.