Understanding how nerve cells help parasitic worms find hosts
Official title: Mapping of chemosensory neuron function to uncover changes in neuronal fates
Funded at California State University Northridge · NIH-10888149 · Data updated 2026-11-12
This study looks at how certain nerve cells in parasitic worms help them find their hosts, which is really important for their survival, and by understanding the genes behind these nerve cells, researchers hope to find new ways to stop these parasites from spreading to people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California State University Northridge NIH-funded |
| Lab location | 1 site (Northridge, United States) |
| Project start | August 2, 2021 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $362,500 |
| NIH project number | 5SC1GM140970-04 |
| Project ID | NIH-10888149 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals at risk of parasitic infections, particularly those in regions where these nematodes are prevalent.
✕Less likely to help
Patients who are not at risk for parasitic infections or those who do not live in affected areas may not benefit from this research.
What this research studies
This research investigates how certain nerve cells in parasitic nematodes help them locate their hosts, which is crucial for their life cycle. By studying a specific nematode species, researchers will explore the genetic factors that influence the development and function of these nerve cells. The approach involves manipulating genes to observe changes in behavior and sensory perception, providing insights into how these organisms adapt to their environments. The findings could lead to new strategies for interrupting the transmission of these parasites to humans.
Why it matters
Potential benefit: If successful, this research could lead to innovative methods for preventing parasitic infections in humans.
How similar studies have gone: Previous research has shown success in understanding the genetic basis of behavior in similar organisms, suggesting that this approach could yield valuable insights.
Where this research is happening
-
California State University Northridge
Northridge, United States Active
Researchers
- Principal investigator: Hong, Ray L — California State University Northridge
- Study coordinator: Hong, Ray L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.