Understanding how Neisseria gonorrhoeae resists antibiotics
Function and regulation of the intrinsic antibiotic resistome of Neisseria gonorrhoeae
This study is looking at how the gonorrhea bacteria become resistant to antibiotics, so we can find better ways to treat the infection, especially in places where options are limited.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10646403 on NIH RePORTER |
What this research studies
This research investigates the mechanisms by which Neisseria gonorrhoeae, the bacteria responsible for gonorrhea, develops resistance to commonly used antibiotics. The team aims to identify the intrinsic systems that enable the bacteria to survive despite antibiotic treatment, particularly in regions where treatment options are limited. By studying these resistance mechanisms, the research seeks to inform the development of new treatment strategies and improve existing therapies for gonorrhea. The findings could provide crucial insights into antibiotic resistance patterns, especially in developing countries where data is scarce.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with gonorrhea, especially those in regions with limited treatment options or high rates of antibiotic resistance.
Not a fit: Patients who do not have gonorrhea or those in regions with effective treatment protocols may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment options for gonorrhea, particularly in areas with high rates of antibiotic resistance.
How similar studies have performed: Previous research has shown success in understanding antibiotic resistance mechanisms in other bacterial infections, suggesting that this approach could yield valuable insights for gonorrhea as well.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Shafer, William Maurice — Emory University
- Study coordinator: Shafer, William Maurice
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.