Understanding how negative self-thoughts and self-compassion relate to suicidal thoughts in young girls

Neural Mechanisms Underlying Self-Critical Rumination and Self-Reassurance and Suicidal Thoughts and Behavior in Youth

NIH-funded research Emma Pendleton Bradley Hospital · NIH-10808197

This study is looking at how the brains of girls aged 12-15 think about themselves, especially when they feel critical or need reassurance, to better understand how these thoughts might relate to feelings of sadness or thoughts about suicide.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionEmma Pendleton Bradley Hospital NIH-funded
Lab location1 site (Riverside, UNITED STATES)
Project IDNIH-10808197 on NIH RePORTER

What this research studies

This research investigates the brain mechanisms that contribute to self-critical thoughts and self-reassurance in adolescent girls aged 12-15, particularly focusing on how these factors relate to suicidal thoughts and behaviors. Using advanced imaging techniques like functional MRI and real-time assessments, the study aims to identify specific brain circuits involved in these processes. By examining these connections, the research seeks to provide insights into the mental health challenges faced by young girls during a critical developmental period.

Who could benefit from this research

Good fit: Ideal candidates for participation are girls aged 12-15 who experience self-critical thoughts or suicidal behaviors.

Not a fit: Patients outside the age range of 12-15 or those who do not experience self-critical thoughts or suicidal behaviors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for preventing suicidal thoughts and behaviors in young girls.

How similar studies have performed: Previous research has shown promising results in understanding the neural mechanisms of self-critical thoughts and their impact on mental health, suggesting that this approach could yield valuable insights.

Where this research is happening

Riverside, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions behavioral disorderBehavior DisordersMental health disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.