Understanding how natural lung components can fight rhinovirus infections
Surfactant Lipid and Protein Inhibition of Rhinovirus Infections
This research explores how natural substances found in the lungs might protect adults, especially those with asthma, from severe common cold viruses.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-11132923 on NIH RePORTER |
What this research studies
Common cold viruses, called rhinoviruses, are a major cause of asthma attacks, particularly a strong type known as RV-C. Our bodies naturally produce special fats and proteins in the lungs, called surfactant, which seem to have anti-viral properties. This project aims to discover how these natural lung components can stop RV-C infections and prevent them from multiplying. We hope to find new ways to protect people from these viruses and reduce asthma flare-ups.
Who could benefit from this research
Good fit: This research is relevant to adults aged 21 and older, especially those who experience asthma exacerbations triggered by rhinovirus infections.
Not a fit: Patients whose asthma exacerbations are not related to rhinovirus infections may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new treatments that use the body's own defenses to prevent or lessen the severity of rhinovirus infections and reduce asthma exacerbations.
How similar studies have performed: Preliminary data from this research and other studies suggest that certain surfactant lipids and proteins can interfere with respiratory viral infections, indicating a promising area of investigation.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Voelker, Dennis R. — University of Arizona
- Study coordinator: Voelker, Dennis R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.