Understanding how natural killer cells respond to HIV
Fine Mechanisms of Adaptive NK Cell Formation Against HIV and SIV
['FUNDING_R01'] · DUKE UNIVERSITY · NIH-11135825
This study is looking at how certain immune cells called natural killer (NK) cells respond to HIV, with the hope of finding better ways to treat the virus by understanding how these cells can remember and target HIV-infected cells.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-11135825 on ClinicalTrials.gov |
What this research studies
This research investigates the role of natural killer (NK) cells in responding to HIV infection. It aims to understand how these immune cells can develop memory and specificity against the virus, potentially leading to more effective treatments. The study will analyze the mechanisms behind NK cell activation and their ability to eliminate HIV-infected cells. By exploring these adaptive immune functions, the research seeks to uncover new strategies for combating HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are interested in understanding their immune response and potential treatment options.
Not a fit: Patients who are not infected with HIV or those who have advanced AIDS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that enhance the body's natural defenses against HIV.
How similar studies have performed: Previous studies have shown promising results in understanding NK cell functions in other viral infections, suggesting potential for success in this area.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: REEVES, ROGER KEITH — DUKE UNIVERSITY
- Study coordinator: REEVES, ROGER KEITH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus