Understanding how natural killer cells respond to COVID-19
Natural Killer cells and the Immunogenetics of COVID-19
['FUNDING_R01'] · UNIVERSITY OF COLORADO DENVER · NIH-10904834
This study is looking at how certain genes might influence the way our immune cells, called natural killer (NK) cells, fight off COVID-19, helping us understand why some people handle the virus better than others, and it could lead to more personalized treatments for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-10904834 on ClinicalTrials.gov |
What this research studies
This research investigates the role of natural killer (NK) cells in the immune response to COVID-19, focusing on how genetic variations affect their function. By examining the interactions between NK cells and specific human genes, the study aims to uncover why some individuals respond better to the virus than others. The research involves analyzing blood samples to assess NK cell activity and genetic profiles, which could lead to insights into personalized treatment strategies for COVID-19 patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have tested positive for COVID-19 and are willing to provide blood samples for analysis.
Not a fit: Patients who have not been infected with COVID-19 or those with underlying conditions that severely compromise their immune system may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of COVID-19 immunity and more effective treatments tailored to individual genetic profiles.
How similar studies have performed: Previous research has shown that understanding genetic variations in immune responses can significantly impact treatment outcomes, suggesting that this approach has potential for success.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NORMAN, PAUL JOHN — UNIVERSITY OF COLORADO DENVER
- Study coordinator: NORMAN, PAUL JOHN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.