Understanding how natural killer cells affect skin inflammation in atopic dermatitis

Natural Killer Cell Regulation of Skin Inflammation

['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11038014

This study is looking at how certain immune cells called natural killer (NK) cells affect skin inflammation in people with atopic dermatitis, with the hope of finding new ways to treat this common skin condition.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11038014 on ClinicalTrials.gov

What this research studies

This research investigates the role of natural killer (NK) cells in regulating skin inflammation associated with atopic dermatitis (AD), a common chronic skin condition. The study aims to identify immune cell types and mechanisms that contribute to AD, focusing on how NK cells can influence type 2 inflammation in the skin. By exploring these immune interactions, the research seeks to fill knowledge gaps that hinder the development of effective therapies for AD. Patients may benefit from new treatment strategies that target these immune regulators.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from atopic dermatitis or related skin inflammatory conditions.

Not a fit: Patients with skin conditions unrelated to atopic dermatitis may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapies that more effectively manage or treat atopic dermatitis.

How similar studies have performed: Previous research has shown promise in targeting immune cells for treating atopic dermatitis, suggesting that this approach may yield significant advancements.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.