Understanding how nanoparticles can overcome biological barriers in medicine

Probing nano/bio interactions to understand and overcome biological barriers limiting nanomedicine

NIH-funded research University of Delaware · NIH-11101263

This study is looking at tiny particles that can help deliver medicine more effectively to treat diseases, making it easier for doctors to target the right cells and improve patient care.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Delaware NIH-funded
Lab location1 site (Newark, UNITED STATES)
Project IDNIH-11101263 on NIH RePORTER

What this research studies

This research focuses on engineering nanoparticles with special properties to improve the treatment of various diseases. By studying how these nanoparticles interact with biological systems, the team aims to enhance their ability to deliver therapies directly to affected cells. The approach includes using nanoparticles to deliver antibodies or nucleic acids that can inhibit disease progression, as well as utilizing light to activate treatments specifically in diseased tissues. The research also explores how the design and packaging of these nanoparticles influence their effectiveness in overcoming biological barriers.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with aggressive cancers, blood disorders, or maternal/fetal health conditions.

Not a fit: Patients with conditions that do not involve the biological barriers targeted by this research may not benefit.

Why it matters

Potential benefit: If successful, this research could lead to more effective and targeted treatments for aggressive cancers and blood disorders.

How similar studies have performed: Previous research has shown promise in using nanoparticles for targeted drug delivery, indicating potential success for this approach.

Where this research is happening

Newark, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Blood Diseasesblood disorderCancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.