Understanding how myopalladin affects heart muscle function and disease
Official title: Myopalladin’s role in cardiac muscle function and disease
Funded at Wichita State University · NIH-10581826 · Data updated 2026-11-12
This study is looking at a protein called myopalladin to see how it affects heart muscle function and how changes in this protein might lead to heart problems, with the hope of finding new treatments that could help patients with heart conditions.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wichita State University NIH-funded |
| Lab location | 1 site (Wichita, United States) |
| Project start | September 1, 2021 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $22,099 |
| NIH project number | 3R15GM140422-01A1S1 |
| Project ID | NIH-10581826 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with cardiomyopathy or those with a family history of heart muscle diseases.
✕Less likely to help
Patients with heart conditions unrelated to myopalladin mutations may not receive benefit from this research.
What this research studies
This research investigates the role of myopalladin, a muscle protein, in the function of heart muscle and its involvement in various heart diseases. The study aims to uncover how mutations in myopalladin contribute to different types of cardiomyopathy, which are conditions that affect the heart muscle's ability to pump blood effectively. By examining the molecular mechanisms and interactions of myopalladin with other proteins in the heart, the research seeks to provide insights that could lead to new therapies for heart-related conditions. Patients may benefit from a better understanding of their condition and potential new treatment options.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for patients suffering from cardiomyopathy and other heart muscle diseases.
How similar studies have gone: Previous research has shown success in understanding the roles of similar proteins in cardiac function, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Wichita State University
Wichita, United States Active
Researchers
- Principal investigator: Beck, Moriah R — Wichita State University
- Study coordinator: Beck, Moriah R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.