Understanding how myopalladin affects heart muscle function and disease
Official title: Myopalladin’s Role in Cardiac Muscle Function and Disease
Funded at Wichita State University · NIH-10292264 · Data updated 2026-11-12
This study is looking at a protein called myopalladin to understand how changes in it can lead to heart muscle diseases, and it aims to find new ways to help people with these conditions.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wichita State University NIH-funded |
| Lab location | 1 site (Wichita, United States) |
| Project start | September 1, 2021 |
| Project end | August 31, 2025 |
| Funding year | 2021 |
| Award (this year) | $428,473 |
| NIH project number | 1R15GM140422-01A1 |
| Project ID | NIH-10292264 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with a family history of cardiomyopathy or those diagnosed with related heart muscle diseases.
✕Less likely to help
Patients with heart conditions unrelated to myopalladin mutations or those without any genetic predisposition to cardiomyopathy may not benefit from this research.
What this research studies
This research investigates the role of myopalladin, a muscle protein, in the function and diseases of the heart. It aims to uncover how mutations in myopalladin contribute to various types of cardiomyopathy, which are heart muscle diseases. By studying the interactions of myopalladin with other proteins in the heart's structure, researchers hope to gain insights that could lead to new therapies for these conditions. The approach involves examining the molecular mechanisms behind sarcomere assembly, which is crucial for heart muscle contraction.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for patients suffering from cardiomyopathies and improve heart muscle function.
How similar studies have gone: Previous research has shown promising results in understanding the role of similar proteins in heart function, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Wichita State University
Wichita, United States Active
Researchers
- Principal investigator: Beck, Moriah R — Wichita State University
- Study coordinator: Beck, Moriah R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.