Understanding how myofibroblasts contribute to skin healing
Deciphering the myofibroblast life cycle in skin wound healing
This study is looking at how special skin cells called myofibroblasts help heal wounds and what happens to them after the healing is done, which could help improve treatments for people who have problems with scarring or healing.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma Medical Research Foundation NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project ID | NIH-11079477 on NIH RePORTER |
What this research studies
This research investigates the life cycle of myofibroblasts, which are cells that play a crucial role in skin wound healing by generating scar tissue. The project aims to understand how these cells are activated during the healing process and what happens to them after the wound has closed. By using advanced techniques to analyze the behavior and characteristics of myofibroblasts, the researchers hope to create a detailed molecular map of their lifecycle. This could lead to insights into both insufficient and excessive wound healing, which can cause significant health issues for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with chronic wounds or those prone to excessive scarring.
Not a fit: Patients with acute wounds that heal normally may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for chronic wounds and better management of scar formation.
How similar studies have performed: Previous research has shown promising results in understanding myofibroblast behavior, indicating that this approach could yield valuable insights.
Where this research is happening
Oklahoma City, United States
- Oklahoma Medical Research Foundation — Oklahoma City, United States (Active)
Researchers
- Principal investigator: Jeong, Sunhye — Oklahoma Medical Research Foundation
- Study coordinator: Jeong, Sunhye
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.