Understanding how myofibroblasts contribute to skin healing
Official title: Deciphering the myofibroblast life cycle in skin wound healing
Funded at Oklahoma Medical Research Foundation · NIH-11079477 · Data updated 2026-11-12
This study is looking at how special skin cells called myofibroblasts help heal wounds and what happens to them after the healing is done, which could help improve treatments for people who have problems with scarring or healing.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma Medical Research Foundation NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $79,756 |
| NIH project number | 5F32AR083823-02 |
| Project ID | NIH-11079477 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with chronic wounds or those prone to excessive scarring.
✕Less likely to help
Patients with acute wounds that heal normally may not receive any benefit from this research.
What this research studies
This research investigates the life cycle of myofibroblasts, which are cells that play a crucial role in skin wound healing by generating scar tissue. The project aims to understand how these cells are activated during the healing process and what happens to them after the wound has closed. By using advanced techniques to analyze the behavior and characteristics of myofibroblasts, the researchers hope to create a detailed molecular map of their lifecycle. This could lead to insights into both insufficient and excessive wound healing, which can cause significant health issues for patients.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for chronic wounds and better management of scar formation.
How similar studies have gone: Previous research has shown promising results in understanding myofibroblast behavior, indicating that this approach could yield valuable insights.
Where this research is happening
-
Oklahoma Medical Research Foundation
Oklahoma City, United States Active
Researchers
- Principal investigator: Jeong, Sunhye — Oklahoma Medical Research Foundation
- Study coordinator: Jeong, Sunhye
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.