Understanding how mustard gas harms the eyes and exploring new treatments
Mechanisms underlying mustard gas-induced conjunctival injury and use of lipid mediators as medical countermeasures
This study is looking into how mustard gas can hurt your eyes and cause ongoing problems like pain and light sensitivity, and it aims to find ways to help heal those injuries and improve treatment options for people affected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Schepens Eye Research Institute NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10882060 on NIH RePORTER |
What this research studies
This research investigates the harmful effects of mustard gas on the eyes, particularly focusing on conjunctival injuries that can cause long-lasting symptoms like eye pain and sensitivity to light. The study aims to uncover the underlying mechanisms of these injuries and how they lead to chronic inflammation and damage to eye tissues. By examining the role of specific lipid mediators that may help in healing and restoring eye health, the research seeks to identify potential therapeutic targets for better treatment options. Patients may be involved in understanding their symptoms and responses to new treatment approaches.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced eye injuries due to mustard gas exposure and are suffering from related symptoms.
Not a fit: Patients with eye injuries from sources other than mustard gas may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from eye injuries caused by mustard gas exposure.
How similar studies have performed: Previous research has shown promise in using lipid mediators for resolving inflammation, suggesting potential success for this approach.
Where this research is happening
Boston, United States
- Schepens Eye Research Institute — Boston, United States (Active)
Researchers
- Principal investigator: Dartt, Darlene a — Schepens Eye Research Institute
- Study coordinator: Dartt, Darlene a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.