Understanding how muscles work and their properties in living organisms
Characterizing Motor Unit Mechanics and Muscle Contractile Properties In Vivo
This study is looking at new ways to see how muscles work while you move, especially for people with conditions like ALS, to help doctors understand muscle health better and catch any problems sooner.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New Jersey Institute of Technology NIH-funded |
| Lab location | 1 site (Newark, United States) |
| Project ID | NIH-10704186 on NIH RePORTER |
What this research studies
This research focuses on developing new techniques to measure how muscles contract and function in real-time, particularly in patients with neuromuscular diseases like Amyotrophic Lateral Sclerosis (ALS). By using advanced methods that can be applied in clinical settings, the study aims to provide better insights into muscle mechanics and potentially identify disease onset earlier. The researchers will explore both neural and muscular interactions to gain a comprehensive understanding of muscle function during voluntary movements.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with neuromuscular diseases, particularly those with Amyotrophic Lateral Sclerosis.
Not a fit: Patients with non-neuromuscular conditions or those who do not have muscle contractility issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better tracking of neuromuscular diseases, improving patient outcomes.
How similar studies have performed: While the approach of using in vivo techniques for muscle characterization is innovative, similar studies have shown promise in understanding muscle mechanics in other contexts.
Where this research is happening
Newark, United States
- New Jersey Institute of Technology — Newark, United States (Active)
Researchers
- Principal investigator: Son, Jongsang — New Jersey Institute of Technology
- Study coordinator: Son, Jongsang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.