Understanding how muscles control voice production in people with vocal fold paralysis

Muscle Control Mechanism of Voice Production in Vocal Fold Paralysis

NIH-funded research Rochester Institute of Technology · NIH-10696434

This study is looking at how the muscles in your voice box work to produce sound, especially for people who have trouble with their vocal cords, and it hopes to find better ways to help improve their voices.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionRochester Institute of Technology NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10696434 on NIH RePORTER

What this research studies

This research investigates the mechanisms by which intrinsic laryngeal muscles control voice production, particularly in individuals with vocal fold paralysis. By utilizing advanced computer modeling and experimental data, the study aims to create a comprehensive dataset that captures the 3D geometry, position, tension, and stiffness of vocal folds during voice production. The goal is to better understand how muscle dysfunction affects voice outcomes, which could lead to improved treatment strategies for those with voice disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with vocal fold paralysis or related voice disorders.

Not a fit: Patients without any vocal fold dysfunction or those with conditions unrelated to voice production may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to enhanced therapies and interventions for individuals suffering from voice production issues due to vocal fold paralysis.

How similar studies have performed: While there has been significant research on voice production, this innovative approach combining 3D modeling and muscle control analysis is relatively novel and has not been extensively tested.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.