Understanding how muscle wasting affects cancer growth
Delineating the contribution of muscle wasting to tumor progression
['FUNDING_R21'] · INDIANA UNIVERSITY INDIANAPOLIS · NIH-10824840
This study is looking at how losing muscle affects cancer growth and patient health, and it aims to find ways to help cancer patients who are also dealing with muscle loss.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | INDIANA UNIVERSITY INDIANAPOLIS (nih funded) |
| Locations | 1 site (INDIANAPOLIS, UNITED STATES) |
| Trial ID | NIH-10824840 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between muscle wasting and tumor progression in cancer patients. It aims to understand how the loss of skeletal muscle impacts the behavior of tumors and the overall health of patients. By studying genetically engineered mice, the researchers will explore how preventing muscle wasting might influence tumor growth and patient outcomes. The goal is to develop more effective therapeutic strategies for cancer patients suffering from muscle wasting.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who are experiencing or at risk of muscle wasting due to their condition.
Not a fit: Patients who do not have cancer or those who are not experiencing muscle wasting may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that enhance survival and quality of life for cancer patients experiencing muscle wasting.
How similar studies have performed: Other research has shown promising results in understanding the effects of muscle wasting on cancer progression, indicating that this approach could yield significant insights.
Where this research is happening
INDIANAPOLIS, UNITED STATES
- INDIANA UNIVERSITY INDIANAPOLIS — INDIANAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DOLES, JASON — INDIANA UNIVERSITY INDIANAPOLIS
- Study coordinator: DOLES, JASON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Oncology Cancer