Understanding how multiple chronic conditions affect Alzheimer's disease using health records
Official title: An end-to-end informatics framework to study Multiple Chronic Conditions (MCC)'s impact on Alzheimer's disease using harmonized electronic health records
Funded at University of Texas Hlth Sci Ctr Houston · NIH-11088288 · Data updated 2026-11-12
This study is looking at how Alzheimer's disease interacts with other long-term health issues by analyzing health records from around 1,000 African American patients, aiming to better understand the risks and patterns that could help improve care for those with Alzheimer's.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 1, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $1,020,991 |
| NIH project number | 5R01AG083039-03 |
| Project ID | NIH-11088288 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include African American individuals aged 65 and older who have been diagnosed with Alzheimer's disease or are at risk for developing it.
✕Less likely to help
Patients without Alzheimer's disease or those who do not have multiple chronic conditions may not benefit from this research.
What this research studies
This research aims to investigate the relationship between Alzheimer's disease and multiple chronic conditions by developing a comprehensive informatics framework. It will utilize harmonized electronic health records (EHRs) to gather and analyze data from approximately 1,000 patients, focusing on African American populations. The study will employ advanced techniques such as natural language processing and computational modeling to identify patterns and predict risks associated with Alzheimer's disease. By creating interoperable EHRs, the research seeks to fill gaps in existing data and enhance our understanding of how chronic conditions influence Alzheimer's progression.
Why it matters
Potential benefit: If successful, this research could lead to improved risk assessment and targeted interventions for patients with Alzheimer's disease and multiple chronic conditions.
How similar studies have gone: Previous research has shown success in using harmonized health records to study chronic conditions, indicating that this approach has potential for meaningful insights.
Where this research is happening
-
University of Texas Hlth Sci Ctr Houston
Houston, United States Active
Researchers
- Principal investigator: Jiang, Xiaoqian — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Jiang, Xiaoqian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.