Understanding how multiple bacteria cause oral diseases
Advancing studies of polymicrobial diseases via streptococcal genetics
['FUNDING_OTHER'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-10839480
This study is looking at how certain bacteria in your mouth team up to cause oral diseases, with the goal of finding better ways to treat infections that don't respond well to regular antibiotics.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON HEALTH & SCIENCE UNIVERSITY (nih funded) |
| Locations | 1 site (PORTLAND, UNITED STATES) |
| Trial ID | NIH-10839480 on ClinicalTrials.gov |
What this research studies
This research investigates the complex interactions between different bacteria that contribute to oral diseases, particularly focusing on how these bacteria work together to enhance their harmful effects. By studying the genetics of specific bacteria found in the mouth, the research aims to uncover the mechanisms behind their virulence and how they can be inhibited. Patients may benefit from new insights into more effective treatments for oral infections that are resistant to traditional antibiotics.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing chronic oral infections or diseases linked to bacterial interactions.
Not a fit: Patients with isolated bacterial infections that do not involve polymicrobial interactions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for patients suffering from polymicrobial oral infections.
How similar studies have performed: Previous research has shown promise in understanding polymicrobial interactions, but this specific approach using genetic models is relatively novel.
Where this research is happening
PORTLAND, UNITED STATES
- OREGON HEALTH & SCIENCE UNIVERSITY — PORTLAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MERRITT, JUSTIN — OREGON HEALTH & SCIENCE UNIVERSITY
- Study coordinator: MERRITT, JUSTIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Disease