Understanding how mucus is produced and transported in the lungs
Mucin Biosynthesis and Transport Mechanisms in Respiratory Health and Disease
['FUNDING_CAREER'] · UNIVERSITY OF COLORADO DENVER · NIH-10810773
This study is looking at how mucus is made and moved in the lungs, especially for people with asthma, to find better ways to help clear thick mucus and improve breathing.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-10810773 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms behind the production and transport of mucus in the respiratory system, particularly in conditions like asthma where mucus becomes thick and difficult to clear. By studying the biology of mucins, which are key components of mucus, the research aims to uncover how these molecules are synthesized and moved within cells. The approach involves examining the cellular processes that affect mucin assembly and transport, which could lead to new therapeutic strategies for respiratory diseases. Patients may benefit from improved treatments that target mucus dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with respiratory diseases such as asthma or other conditions that involve mucus obstruction.
Not a fit: Patients with respiratory conditions that do not involve mucus dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective therapies for patients suffering from respiratory conditions characterized by mucus dysfunction.
How similar studies have performed: Previous research has shown promise in understanding mucin biology, but this specific approach to studying mucin transport mechanisms is relatively novel.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JARAMILLO HERNANDEZ, ANA MARIA — UNIVERSITY OF COLORADO DENVER
- Study coordinator: JARAMILLO HERNANDEZ, ANA MARIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.