Understanding how movement is controlled in health and disease

Neural basis of movement in health and disease

NIH-funded research Fred Hutchinson Cancer Center · NIH-10930140

This study is looking at how our bodies control movement and what happens when that control is affected by neurological disorders or injuries, using tiny worms to learn more about how movement works, which could eventually help people with movement problems.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionFred Hutchinson Cancer Center NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-10930140 on NIH RePORTER

What this research studies

This research investigates the molecular mechanisms that govern movement and how these processes can be disrupted by neurological disorders and injuries. By using advanced techniques such as genetics and imaging, the study focuses on understanding motor regulation in living animals, specifically the model organism C. elegans. The research aims to uncover essential principles of locomotor behavior development and adaptation, which could lead to new insights into movement disorders. The findings may help identify potential therapeutic targets for improving movement in affected individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing movement disorders or neurological conditions that affect locomotion.

Not a fit: Patients with non-neurological conditions or those who do not experience movement-related issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments for movement disorders, enhancing the quality of life for patients affected by such conditions.

How similar studies have performed: Previous research has shown success in using model organisms like C. elegans to uncover fundamental principles of movement, suggesting that this approach is promising.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.