Understanding how motor skills become stable over time

Molecular mechanisms of motor skill stabilization

NIH-funded research University of California Santa Cruz · NIH-10943832

This study is looking at how young birds learn to sing and how their brains help them become better at it over time, which could help us understand and improve treatments for people with motor skill challenges like walking or talking.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Santa Cruz NIH-funded
Lab location1 site (Santa Cruz, United States)
Project IDNIH-10943832 on NIH RePORTER

What this research studies

This research investigates the molecular mechanisms that help stabilize motor skills, such as walking and talking, which are learned during early development. By studying the song of the Bengalese finch, a bird known for its complex vocalizations, researchers aim to uncover how neural circuits transition from variable to stable performance. The project utilizes advanced genomic techniques and single-cell molecular assays to analyze the changes in these circuits over time. Patients may benefit from insights gained about motor skill stabilization that could inform therapies for motor skill disorders.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit include individuals with developmental motor skill disorders or conditions affecting motor performance.

Not a fit: Patients with purely cognitive or non-motor-related conditions may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapies for improving motor skill learning and stability in individuals with motor skill disorders.

How similar studies have performed: While the specific approach of this research is novel, similar studies in animal models have shown promise in understanding motor skill learning and stabilization.

Where this research is happening

Santa Cruz, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.