NIH-funded research NIH-funded research

Understanding how motor learning affects people with psychosis

Official title: Longitudinal Assessment of Distinct Motor Learning Processes to Inform Mechanistic Models of Sensorimotor Function in Psychosis

Funded at Trustees of Indiana University · NIH-10984412 · Data updated 2026-11-12

This study is looking at how learning to move and use your body might be connected to symptoms like delusions and hallucinations in people with psychosis, with the hope of finding new ways to help improve treatment for these symptoms.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionTrustees of Indiana University
NIH-funded
Lab location1 site (Bloomington, United States)
Project startAugust 1, 2024
Project endJuly 31, 2029
Funding year2024
Award (this year)$202,840
NIH project number1K23MH135215-01A1
Project IDNIH-10984412 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with psychosis who experience motor disturbances.

Less likely to help

Patients without a diagnosis of psychosis or those who do not exhibit motor learning deficits may not benefit from this research.

What this research studies

This research investigates the relationship between motor learning processes and psychotic symptoms in individuals diagnosed with psychosis. By examining how sensorimotor functions are altered in these patients, the study aims to identify the underlying mechanisms that contribute to symptoms like delusions and hallucinations. The approach includes longitudinal assessments and advanced computerized models to analyze motor learning and its impact on behavior. This research seeks to bridge critical knowledge gaps that could lead to new treatment targets for psychosis.

Why it matters

Potential benefit: If successful, this research could lead to improved interventions for patients with psychosis by targeting motor learning processes.

How similar studies have gone: Other research has shown promising results in understanding the link between motor functions and psychiatric symptoms, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Trustees of Indiana University
    Bloomington, United States
    Active

Researchers

  • Principal investigator: Moussa-Tooks, Alexandra — Trustees of Indiana University
  • Study coordinator: Moussa-Tooks, Alexandra

Related research

Other NIH-funded projects on the same topics.

  • Psychosis in diverse settings across the world

    This project studies how psychotic disorders show up and respond to treatment in adults with diverse backgrounds, including populations in Africa, the Caribbean, and other Global South settings.

    NIH research Suny Downstate Medical Center · Brooklyn, United States · NIH-11592428

  • Psychosis in Diverse Settings: Understanding Symptoms and Treatment Across Global South

    A human-facing study will look at how psychotic disorders present and respond to treatment in adults from Africa, the Caribbean, and other Global South settings, using genetic and clinical data.

    NIH research Suny Downstate Medical Center · Brooklyn, United States · NIH-11592427

  • A new online brain-scan-style tool to spot early psychosis risk

    A new online-based set of tasks and a computer model aims to identify people at high risk for developing psychosis earlier and more accurately.

    NIH research Northwestern University · Chicago, United States · NIH-11590585

  • Genetic clues for early-onset psychosis in Latino youth

    This project looks at the genes of young people with early-onset psychosis and compares them with similar youths without psychosis to find genetic factors that contribute to the illness.

    NIH research Boston Children's Hospital · Boston, United States · NIH-11554752

  • Biomarkers to tailor rehab for Veterans with schizophrenia

    A clinician-scientist is developing a brain-based biomarker to guide personalized rehabilitation for Veterans with schizophrenia.

    NIH research VA San Diego Healthcare System · San Diego, United States · NIH-11552825

  • Computational analysis of facial expression in early psychosis

    Aims to develop computer-based measures of facial expression in people at risk for or with schizophrenia to help track symptoms and guide future trials.

    NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11539126

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.