Understanding how mood states are linked to brain activity and behavior
Official title: Behavioral and Neuronal Correlates of Human Mood States
Funded at Stanford University · NIH-10982498 · Data updated 2026-11-12
This study is looking at how your speech and facial expressions can help track your mood in real-time, especially for people getting ready for epilepsy surgery, so that doctors can better understand and support your mental health.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $196,860 |
| NIH project number | 5R21MH134172-02 |
| Project ID | NIH-10982498 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with epilepsy who also have major depression and are undergoing surgical treatment.
✕Less likely to help
Patients without epilepsy or those who do not have comorbid major depression may not benefit from this research.
What this research studies
This research investigates how observable behaviors, such as speech patterns and facial expressions, can provide continuous and objective measures of mood. By using advanced video technology, the study aims to correlate these behaviors with brain activity in patients undergoing epilepsy surgery. Participants will have their mood assessed frequently while their audio-visual data is collected, allowing researchers to develop a model that predicts mood changes based on these behaviors. The goal is to improve mental health treatment by providing more accurate and timely assessments of mood.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring and treatment of mood disorders, enhancing patient care.
How similar studies have gone: Other research has shown promise in using behavioral indicators to assess mood, but this approach is innovative in its use of video-derived data in a clinical setting.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Keller, Corey J — Stanford University
- Study coordinator: Keller, Corey J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.