Understanding how molecules are organized within cells and their impact on cell functions
Official title: Dissecting subcellular and cellular organization by spatial molecular neighborhood networks
Funded at Georgia Institute of Technology · NIH-10932871 · Data updated 2026-11-12
This study is looking at how the way molecules are arranged inside cells affects how those cells grow and change, which could help us understand how they respond to different treatments and conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | September 22, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $372,051 |
| NIH project number | 5R35GM151028-02 |
| Project ID | NIH-10932871 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve abnormal cellular functions or tissue-specific diseases.
✕Less likely to help
Patients with stable, well-understood cellular functions or those not affected by tissue-specific abnormalities may not benefit from this research.
What this research studies
This research investigates the organization of molecules within cells, focusing on how their spatial arrangement affects essential cell functions like growth and differentiation. By examining the neighborhoods of RNAs and proteins, the study aims to uncover how these arrangements influence cellular responses to various stimuli and drugs. The approach involves advanced imaging techniques and multiplexed measurements to analyze these molecular neighborhoods in detail, which could lead to a better understanding of tissue-specific functions and abnormalities.
Why it matters
Potential benefit: If successful, this research could lead to new insights into cellular behavior and improve treatment strategies for diseases by targeting specific molecular interactions.
How similar studies have gone: Previous studies have shown promise in understanding molecular neighborhoods, but this research aims to establish a more comprehensive and detailed model, making it a novel approach.
Where this research is happening
-
Georgia Institute of Technology
Atlanta, United States Active
Researchers
- Principal investigator: Coskun, Ahmet F. — Georgia Institute of Technology
- Study coordinator: Coskun, Ahmet F.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.