Understanding how mitochondrial dysfunction affects neurological diseases
Mitochondrial Integrated Stress Response in Neurological Diseases
This study is looking at how problems with tiny parts of our cells called mitochondria might play a role in diseases like Alzheimer's and Parkinson's, with the hope of finding new ways to help people who are dealing with these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11080318 on NIH RePORTER |
What this research studies
This research investigates the role of mitochondria in neurological diseases, particularly focusing on how their dysfunction contributes to conditions like Alzheimer's and Parkinson's disease. By exploring the complex metabolic pathways and genetic factors involved, the research aims to uncover new therapeutic approaches to mitigate the effects of mitochondrial dysfunction. Patients may benefit from insights that could lead to innovative treatments for age-related neurodegenerative disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with age-related neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, or ALS.
Not a fit: Patients with non-neurological conditions or those without age-related neurodegenerative disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve the quality of life for patients suffering from neurodegenerative diseases.
How similar studies have performed: Previous research has shown promising results in understanding mitochondrial dysfunction in neurological diseases, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Manfredi, Giovanni — Weill Medical Coll of Cornell Univ
- Study coordinator: Manfredi, Giovanni
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.