Understanding how mitochondria respond to burn injuries
The Role of the Mitochondrion in the Metabolic Stress Response to Burn Trauma
This study is looking at how burn injuries affect the tiny powerhouses in our cells, called mitochondria, and how this impacts energy use and fat storage, with the hope of finding better ways to help people recover from burns and avoid problems like muscle loss and insulin resistance.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arkansas Children's Hospital Res Inst NIH-funded |
| Lab location | 1 site (Little Rock, United States) |
| Project ID | NIH-11099359 on NIH RePORTER |
What this research studies
This research investigates how mitochondria, the energy-producing structures in cells, react to the stress caused by burn injuries. By using innovative animal models, the study aims to trace how energy metabolism and fat distribution are affected after burns. The goal is to uncover mechanisms that lead to complications like insulin resistance and muscle loss in burn survivors, ultimately seeking to improve recovery strategies for these patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced significant burn injuries and are facing challenges in their recovery.
Not a fit: Patients with minor burns or those who have fully recovered from their injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance recovery and quality of life for burn survivors.
How similar studies have performed: Previous research has shown promising results in understanding metabolic responses to trauma, indicating that this approach could yield valuable insights.
Where this research is happening
Little Rock, United States
- Arkansas Children's Hospital Res Inst — Little Rock, United States (Active)
Researchers
- Principal investigator: Porter, Craig — Arkansas Children's Hospital Res Inst
- Study coordinator: Porter, Craig
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.