Understanding how mitochondria move and function in cells
Regulation of mitochondrial dynamics pathways in mammalian cells
['FUNDING_OTHER'] · UNIVERSITY OF COLORADO DENVER · NIH-11081635
This study is looking at how tiny powerhouses in our cells, called mitochondria, move and work together, especially in non-nerve cells, to help us understand their role in health and diseases like cancer and aging, which could lead to better treatments for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-11081635 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms that control mitochondrial dynamics, which are essential for cell function and health. By examining how mitochondria transport and communicate within different cell types, particularly non-neuronal cells, the study aims to uncover the roles of specific proteins in these processes. The research will utilize advanced cellular biology techniques to analyze mitochondrial behavior and its impact on cell movement and signaling. Patients may benefit from insights gained about mitochondrial function in various diseases, including cancer and age-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions related to mitochondrial dysfunction, such as certain cancers or age-related disorders.
Not a fit: Patients with conditions unrelated to mitochondrial function or those who do not have any mitochondrial-related diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for diseases linked to mitochondrial dysfunction.
How similar studies have performed: Previous research has shown promising results in understanding mitochondrial dynamics in neurons, suggesting potential for success in exploring these mechanisms in other cell types.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CAINO, MARIA CECILIA — UNIVERSITY OF COLORADO DENVER
- Study coordinator: CAINO, MARIA CECILIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers