Understanding how mitochondria maintain their functions and health
Mitochondrial Fidelity and Homeostasis
This study is looking at how tiny parts of our cells called mitochondria help keep our cells healthy and how they react to stress, which could help us understand and find new treatments for age-related diseases like Parkinson's and Alzheimer's.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Lincoln NIH-funded |
| Lab location | 1 site (Lincoln, United States) |
| Project ID | NIH-11011188 on NIH RePORTER |
What this research studies
This research investigates the role of mitochondria, the energy-producing organelles in our cells, in maintaining their functions and health. It aims to uncover how these organelles respond to stress and physiological changes, which is crucial for understanding various age-related diseases like Parkinson's and Alzheimer's. By using a multidisciplinary approach, the research seeks to identify mechanisms that ensure mitochondrial stability and function, potentially leading to new therapeutic strategies. Patients may benefit from insights gained about mitochondrial health and its impact on neurodegenerative conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing age-related neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, or other related conditions.
Not a fit: Patients with non-age-related conditions or those without mitochondrial dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for age-related neurodegenerative diseases by improving mitochondrial function.
How similar studies have performed: Other research has shown promise in understanding mitochondrial function and its implications for neurodegenerative diseases, indicating that this approach could yield valuable insights.
Where this research is happening
Lincoln, United States
- University of Nebraska Lincoln — Lincoln, United States (Active)
Researchers
- Principal investigator: Khalimonchuk, Oleh — University of Nebraska Lincoln
- Study coordinator: Khalimonchuk, Oleh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.