Understanding how mitochondria influence lung cancer spread
Investigation of a mitochondria-associated metastasis regulatory mechanism
This study is looking at how a certain gene affects the spread of lung cancer, with the hope of finding new ways to slow down or stop the disease for patients dealing with metastatic lung cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10918078 on NIH RePORTER |
What this research studies
This research investigates the biological mechanisms behind lung cancer metastasis, which is a leading cause of cancer-related deaths. The team aims to explore how a specific gene related to autophagy affects the spread of lung cancer through its interactions with mitochondria. By manipulating this gene's expression, the researchers hope to find ways to inhibit the progression of lung cancer. The findings could lead to new therapeutic strategies for treating patients with metastatic lung cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with lung cancer, particularly those with metastatic disease.
Not a fit: Patients with non-cancerous conditions or those without lung cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that significantly improve survival rates for lung cancer patients.
How similar studies have performed: Previous research has shown promise in targeting metabolic pathways in cancer, suggesting that this approach could yield significant insights and advancements.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Mc Niven, Mark a. — Mayo Clinic Rochester
- Study coordinator: Mc Niven, Mark a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.