Understanding how mitochondria are positioned in mature neurons.
The role and regulation of mitochondrial localization in mature neurons.
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-10994168
This study looks at how brain cells move tiny energy factories called mitochondria to keep them healthy, especially as we age or after an injury, and it hopes to find ways to help prevent or lessen problems like Alzheimer's disease.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-10994168 on ClinicalTrials.gov |
What this research studies
This research investigates how neurons manage the location of mitochondria, which are crucial for energy supply and overall cell health. It focuses on the signaling mechanisms that control mitochondrial positioning in response to various stimuli, particularly in the context of aging and injury. By studying these processes, the research aims to uncover how proper mitochondrial localization can support neuronal function and potentially prevent or mitigate neurological disorders like Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old, particularly those experiencing age-related neurological changes or conditions such as Alzheimer's disease.
Not a fit: Patients with neurological conditions unrelated to mitochondrial dysfunction or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating or preventing neurodegenerative diseases by improving mitochondrial function in neurons.
How similar studies have performed: Previous research has shown promising results in understanding mitochondrial dynamics in neurons, suggesting that this approach could yield valuable insights.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HAN, SUNG MIN — UNIVERSITY OF FLORIDA
- Study coordinator: HAN, SUNG MIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.