Understanding how mitochondria affect metabolism after burn injuries
The Role of the Mitochondrion in the Metabolic Stress Response to Burn Trauma
This study looks at how the tiny energy factories in our cells, called mitochondria, react to the stress of burn injuries, and it aims to understand how this affects fat and muscle in order to help burn survivors recover better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arkansas Children's Hospital Res Inst NIH-funded |
| Lab location | 1 site (Little Rock, United States) |
| Project ID | NIH-10873822 on NIH RePORTER |
What this research studies
This research investigates how mitochondria, the energy-producing structures in cells, respond to the metabolic stress caused by burn trauma. By using innovative rodent models, the study aims to trace how specific types of fat and muscle tissue change and function after burns. The goal is to uncover mechanisms that lead to complications like insulin resistance and muscle loss in burn survivors, ultimately seeking to improve recovery strategies for these patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced significant burn injuries and are facing challenges in their recovery process.
Not a fit: Patients with minor burns or those who have fully recovered from their injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance recovery and quality of life for burn survivors.
How similar studies have performed: Previous research has shown promising results in understanding metabolic responses to trauma, but this specific focus on mitochondrial roles in burn recovery is relatively novel.
Where this research is happening
Little Rock, United States
- Arkansas Children's Hospital Res Inst — Little Rock, United States (Active)
Researchers
- Principal investigator: Porter, Craig — Arkansas Children's Hospital Res Inst
- Study coordinator: Porter, Craig
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.