Understanding how mineral metabolism affects kidney, heart, and bone health
Investigating causality between abnormalities of mineral metabolism and kidney, cardiovascular and bone disease
This study is looking at how problems with minerals in the body might be linked to issues with the kidneys, heart, and bones, and it’s for anyone interested in understanding how these health conditions are connected and what could help treat them better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10671761 on NIH RePORTER |
What this research studies
This research investigates the relationship between mineral metabolism abnormalities and diseases affecting the kidneys, heart, and bones. By using a method called Mendelian Randomization, the study aims to determine whether specific mineral metabolism biomarkers are directly responsible for these health complications. The research will analyze genetic data to identify which biomarkers may be the most effective targets for treatment. Ultimately, the goal is to enhance our understanding of how these factors interact and to inform future clinical applications.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with chronic kidney disease or those at risk for cardiovascular and bone diseases.
Not a fit: Patients without any abnormalities in mineral metabolism or those not affected by kidney, cardiovascular, or bone diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for patients with kidney, cardiovascular, and bone diseases.
How similar studies have performed: Previous research using Mendelian Randomization has shown promise in establishing causal relationships in various health conditions, suggesting that this approach could yield valuable insights.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Robinson-Cohen, Cassianne — Vanderbilt University Medical Center
- Study coordinator: Robinson-Cohen, Cassianne
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.