Understanding how microtubules transport materials in cells
Mechanisms of microtubule-based transport
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10875292
This study is looking at how tiny structures in our cells help move important parts around, which is really important for keeping our cells healthy, and it hopes to find new ways to help people with neurological diseases caused by problems with this movement.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10875292 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms of microtubule-based transport within eukaryotic cells, which is crucial for maintaining cellular organization and function. The team employs a variety of advanced techniques, including cryo-electron microscopy and live-cell imaging, to study how proteins like dynein facilitate the movement of cellular components. By examining these processes at molecular and cellular levels, the research aims to uncover insights into the causes of neurological diseases linked to transport defects. Patients may benefit from a deeper understanding of these mechanisms, potentially leading to new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with degenerative neurological disorders linked to microtubule dysfunction.
Not a fit: Patients with conditions unrelated to microtubule transport mechanisms may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for neurological disorders caused by transport defects in cells.
How similar studies have performed: Previous research has shown success in understanding similar transport mechanisms, indicating that this approach has potential for significant findings.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RECK-PETERSON, SAMARA L — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: RECK-PETERSON, SAMARA L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.