Understanding how microtubules help cells divide correctly
Mechanics of Microtubule Aster Growth and Positioning
['FUNDING_R01'] · UNIVERSITY OF WYOMING · NIH-10674011
This study looks at how tiny structures called microtubules help organize cells during division, which is important for making sure everything goes smoothly, especially in larger cells after fertilization.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WYOMING (nih funded) |
| Locations | 1 site (LARAMIE, UNITED STATES) |
| Trial ID | NIH-10674011 on ClinicalTrials.gov |
What this research studies
This research investigates the role of microtubules in organizing the internal structure of cells, particularly during cell division. It focuses on how microtubule asters, which are structures formed by microtubules, move to the center of the cell and help position the cell division machinery. By studying these processes, the research aims to uncover the forces involved in microtubule positioning and their impact on cell division accuracy. This could provide insights into how errors in cell division occur, especially in large cells after fertilization.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cell division errors, such as certain developmental disorders or cancers.
Not a fit: Patients with stable conditions unrelated to cell division or microtubule function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of cell division errors that contribute to developmental issues and diseases.
How similar studies have performed: While the specific approach may be novel, similar studies have shown that understanding microtubule dynamics can lead to significant advancements in cell biology.
Where this research is happening
LARAMIE, UNITED STATES
- UNIVERSITY OF WYOMING — LARAMIE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GATLIN, JESSE C — UNIVERSITY OF WYOMING
- Study coordinator: GATLIN, JESSE C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.