Understanding how microtubules function in cells
Official title: Biology and Biochemistry of the Microtubule Cytoskeleton
Funded at University of Michigan at Ann Arbor · NIH-11061796 · Data updated 2026-11-12
This study looks at tiny structures in our cells called microtubules and how they work with special proteins to help cells divide properly, which is important for everyone’s health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $385,950 |
| NIH project number | 5R35GM153209-02 |
| Project ID | NIH-11061796 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve cellular dysfunction, such as cancer or neurodegenerative diseases.
✕Less likely to help
Patients with conditions unrelated to cellular processes or microtubule function may not benefit from this research.
What this research studies
This research investigates the biology and biochemistry of microtubules, which are essential components of the cellular structure. It focuses on how microtubule-associated proteins and motor proteins interact with microtubules to facilitate critical cellular processes, especially during cell division. The study employs advanced techniques to explore the assembly of microtubules and their modifications under various conditions, aiming to uncover new pathways and mechanisms that regulate their function.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for diseases related to cell division and cytoskeletal dysfunction.
How similar studies have gone: Previous research has shown promising results in understanding microtubule dynamics and their role in cellular processes, indicating that this area of study has potential for significant advancements.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Ohi, Ryoma — University of Michigan at Ann Arbor
- Study coordinator: Ohi, Ryoma
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.